Carolyn is the Executive Director of OpenBiome. She was a member of the founding team and previously served as Director of Outreach and Public Affairs, where she oversaw OpenBiome's efforts to expand the availability of FMT across 1,000 hospitals and clinics, present its work to the public, and contribute to the discourse on the regulation of fecal microbiota.
Previously, Carolyn worked at the US Agency for International Development, where she helped launch the Global Innovation Fund, a $200 million institution backed by foreign aid agencies from the US, UK, Canada, Australia, Sweden, and South Africa to test and support low-cost, high-impact interventions to improve global health and prosperity.
She holds an MPA and a BA from Princeton University's Woodrow Wilson School of Public and International Affairs, where she was awarded the Scholars in the Nation's Service Initiative (SINSI) Fellowship, a four-year program to support outstanding individuals to launch careers in public service.
Scott Olesen, PhD
Scott is Scientific Director for OpenBiome. He was previously a Postdoctoral Fellow at the Harvard T. H. Chan School of Public Health, where his research focused on how population-wide antibiotic use affects antibiotic resistance. Scott earned his PhD from MIT, where his graduate work focused on the design of clinical trials for FMT, human microbiome analysis, and environmental microbiology ecosystem modeling. He holds an MPhil and MASt from the University of Cambridge and a BA from Williams College.
Majdi Osman, MD MPH
Majdi is the Clinical Program Director at OpenBiome. He is an Internal Medicine physician who trained at University College London.
He previously worked at the World Health Organization and completed his Master's in Public Health at the Harvard T.H.Chan School of Public Health on a Frank Knox Fellowship. He was trained in tropical medicine and infectious diseases at the London School of Hygiene and Tropical Medicine (LSHTM) and has taught and practiced medicine throughout Africa. He co-founded YBank, a non-profit dedicated to adolescent health. His research focuses on infectious diseases, quality improvement and clinical safety. He is excited to be part of OpenBiome in its mission to deliver safe access to FMT.
Jim Sigler, MBA, has 28+ years of experience in drug development. At Genzyme, he and his team brought Carticel™, the first biologic therapy of its type, from academia all the way through FDA submission, inspection, licensure, and commercialization. At Reprogenesis, he and his team executed a crash re-formulation and pre-clinical model development effort that resulted in the resumption of a Phase III trial less than nine months after suspending the trial. At Acceleron, he and his team completed in-house manufacture of the first clinical drug substance for the company, and the outside manufacture of clinical drug product, less than two years after the company’s initial financing and barely seventeen months after board approval to build the in-house capability.
Jim received his BS in Biology/General Studies from Cornell University and his MBA from Harvard Business School.
Steve is the Interim Chief Operating Officer of OpenBiome.
He has been a venture capitalist, CEO, and entrepreneur, and has 20 years of experience funding innovation across healthcare, from research through clinical to commercial. As Managing Director, of the Novartis Venture fund for twelve years, he was actively engaged in all investment decisions across the portfolio, managed the medical device practice, while also investing in biotech.
Prior to Novartis, Steve was on the life science team at Prism Venture Partners, where he focused on medical devices. He started in venture capital as a Kauffman Fellow with Mid-Atlantic Venture Funds, where he focused on software startups. He started his career as a turn-around CEO, buying a defunct industrial distribution business out of bankruptcy, and rebuilding it over the next five years. He also was Interim-CEO of Rox Medical, a venture funded device company developing a therapy for hypertension.
Steve holds an M.B.A. with distinction from the University of Michigan Business School and a B.S. in mechanical engineering from Columbia University's School of Engineering and Applied Science.
Delasie is the Associate Director of Manufacturing at OpenBiome. He oversees and develops the strategy for the Production, Training, and Materials departments. Delasie studied biomedical laboratory sciences at Boston University School of Medicine, and comes to OpenBiome with a background of training and process improvements in various biologics.
Michael is the Director of Clinical Outreach at OpenBiome. He graduated from North Carolina State University with a degree in Business Administration with concentrations in Marketing and Human Resource Management. Michael has vast experience managing major hospital and pharmaceutical accounts, and is excited to help grow existing and future relationships with OpenBiome partners!
Emily is the Director of External Affairs at OpenBiome, overseeing all outward facing communications, including to researchers, clinicians, patients, media, and the general public.
She previously worked at the White House under President Obama for seven years, where she most recently served as Associate Staff Secretary. In that role, she worked with the highest levels of government to manage and direct the flow of all written materials that crossed the President's desk. In prior White House roles, she worked at the Office of Management and Budget and the Office of Health Reform.
She then returned to her roots in scientific research and health care, and coordinated clinical trials in the NICU at Brigham and Women’s Hospital before beginning her work at OpenBiome. She is thrilled to continue her deep commitment to expanding access to health care. She holds an MA and a BA in Neuroscience from Wesleyan University.
Ken Linde is the Director of IT for OpenBiome. He graduated from the University of Washington with a degree in Business Administration. Ken has over 20 years of experience in Director and Senior level IT roles in the fast paced world of start-ups. He has been part of the founding teams that have launched eCommerce sites, SaaS products, mobile apps and a documentary film. Ken is excited to help OpenBiome make effective use of technology in our mission to expand research and patient access to FMT.
Gina is the Director of Product Operations at OpenBiome. She currently oversees the FMT supply chain and development of information systems & internal operations.
Gina joined the OpenBiome team in 2014 to lead the development of FMT capsules. Since then, she has leveraged her experience with cross-functional decision making, problem solving, and design to expand the world’s access and understanding of the power of poop. She holds a BA from Middlebury College in Economics and Biochemistry.
Rob is the Director of Strategic Initiatives and Development. In this role he helps guide the strategic direction of the organization and build the partnerships necessary to accomplish our mission. He leads OpenBiome's fundraising efforts, which include a combination of research grants and philanthropic gifts. He was previously the Director of Research Operations at OpenBiome.
Prior to his time at OpenBiome, he worked at the Center for International Development at the Harvard Kennedy School as a Program Manager, where he oversaw a broad range of research projects, including field-based RCTs and a pool of funding for exploratory researcher-policymaker engagements.
He is a co-founder of the Philani Family Fund, which provides emergency housing and scholarships for impoverished women in the informal settlements around Cape Town, South Africa, and formerly served as the Regional Director for Children of South Africa (CHOSA, Inc), a US-based non-profit organization that helps community-based organizations better serve orphans and vulnerable children.
He holds a Master in Public Affairs degree from the Woodrow Wilson School at Princeton University and a BA in history from Colby College.
Jeannette van der Velde
Jeannette van der Velde is the Director of Clinical Research Operations at OpenBiome where she provides high-level oversight and direction of the clinical research team in both OpenBiome- and Investigator-sponsored trials. She previously worked at the Massachusetts General Hospital Cancer Center Protocol Office as Senior Clinical Research Program Manager. In this role, she led the Lymphoma and Multiple Myeloma clinical trial teams and concurrently launched a disease-agnostic Cellular Therapy clinical research group, overseeing a combined portfolio of nearly 100 clinical trials.
She co-founded the Sweet Life School, which provides elementary education to children in rural Cambodia and served as a consultant with the American Society for Clinical Pathologists when they were asked by the Namibian Institute of Pathology to improve laboratory HIV-detection and anti-retroviral treatment monitoring.
She holds a MPH from Johns Hopkins School of Public Health (focusing on International Health and Health Policy) and a MSc. in Health Promotion and Health Education from the University of Alberta, Canada.
Lisa Serwin has a 25+ year career leading start-ups and established organizations in the healthcare, consumer product and retail sectors. She is currently the Co-Founder of C-Sweetener, a nonprofit that matches senior women in the healthcare industry with mentors so they can thrive in C-suite leadership positions.
Lisa has served as CEO and in other leadership roles at a wide variety of technology and healthcare companies, where her responsibilities have ranged from strategic planning to closing on multiple rounds of financing. In 2005, Lisa ran the Commission on Medical Research, Education and Training for the State of Nevada. Lisa has also served on multiple for- and not-for-profit boards.
She is an author and recognized expert in healthcare technology and personal finance, and has been featured by Wired.com, Forbes.com, SheKnows, Huffington Post, CBS Radio, NPR, Popular Science and others. She is a member of Life Sciences Angels.
She has an M.B.A. from Loyola Marymount University and B.A. from U.C.L.A.
Jim Bildner, JD
Jim is the CEO of the DRK Foundation, and he brings more than 30 years of experience in the public, private and nonprofit sectors. He is an Adjunct Lecturer in Public Policy at the Harvard Kennedy School of Government, as well as a Senior Research Fellow at the Center for Public Leadership and Hauser Center Institute for Nonprofit Organizations at Harvard University. Jim serves on the boards of numerous foundations and organizations, has served as CEO of two public companies, and is a member of the Bar of the Commonwealth of Massachusetts.
Charles Hewett, PhD
Charles Hewett, PhD is currently an independent consultant serving as the Executive Director of the Institute for Digital Engineering and Life Sciences (IDEALS) in Portland, Maine. Earlier this month, he retired as executive vice president at The Jackson Laboratory where he served as Chief Operating Officer for nearly 15 years. He oversaw the launch of numerous research products and services; modernization of mouse production facilities; completion of new research laboratories in Maine, the creation of Jax Genomic Medicine in Connecticut, and the relocation and expansion of the Laboratory's California operation. Chuck remains a member of the Laboratory's Board of Trustees and serves as a board member of several other non-profit and for-profit organizations.
Chuck previously served as CEO of Atlantic Energy Partners and Neptune Regional Transmission System, while concurrently vice president and secretary to the Board of the Cianbro Companies. Chuck served for three years as the COO of the Executive Branch of the state of Maine during Gov. Angus King's first term. He has held chief executive posts in the international pharmaceutical industry, in electric generation, and in natural resource management, and has created companies, managed start-up projects, and completed successful turnarounds in Asia, Europe, and the United States.
Neil is a Senior VP of Innovation for Schneider Electric. He establishes the technology direction for the world’s largest R&D budget devoted to power, cooling, and rack infrastructure for data centers. Neil holds 28 patents related to high-efficiency and high-density data center power and cooling infrastructure, and has published over 60 papers related to power and cooling systems, many published in more than 10 languages, most recently with a focus on the improvement of energy efficiency. He is an internationally recognized keynote speaker on the subject of high-efficiency data centers. Neil is currently working to advance the science of high-efficiency, high-density, scalable data center infrastructure solutions and is a principal architect of the APC InfraStruXure system. After founding APC in 1981, Neil served as Senior VP of Engineering and CTO for 26 years, assuming his current role after APC joined Schneider Electric in 2007. He received his bachelors and masters degrees in electrical engineering from MIT.
Jane Williams, MD MPH
Jane has recently joined the Health and Medical Management team as a Medical Director at Blue Cross Blue Shield of Massachusetts working with the Alternate Quality Contract Support team and supporting contracting, credentialing and corporate peer review committees. She practiced family medicine for 14 years in the Merrimack Valley. Most recently, Jane worked as a medical director at Parexel International providing scientific and strategic guidance to clients as well as supporting protocol development, regulatory submissions, evaluation of new technologies and safety monitoring. Jane earned her undergraduate degree from Dartmouth College, her doctor of medicine at Albany Medical College of Union University and a master’s degree in public health from the Harvard School of Public Health.
Eric Alm, PhD
Eric is an Associate Professor of Biological Engineering at MIT and an Associate Member of the Broad Institute. He holds degrees in Mathematics/Computer Science, Biology, and Biochemistry, and his current research covers diverse topics ranging from biofuels to human disease. He is passionate about using scientific discoveries and new technologies to solve real-world problems, and thrilled that OpenBiome provides an opportunity to translate human microbiome research into therapies that improve patients' lives.
Jessica Allegretti, MD MPH
Dr. Allegretti is a gastroenterologist at Brigham and Women’s Hospital with both clinical and research interests in Clostridium difficile infection and inflammatory bowel disease. She founded and coordinates the fecal transplant program for recurrent Clostridium difficile infections at BWH. She completed her internal medicine residency at Massachusetts General Hospital and her fellowship in gastroenterology at Brigham and Women’s Hospital. She also completed her Master’s in Public Health at Harvard T.H. Chan School of Public Health.
Zain Kassam, MD MPH FRCPC
Dr. Zain Kassam is a special advisor to OpenBiome, and was the Chief Medical Officer until January 2018. He is a gastroenterologist, internal medicine physician and epidemiologist.
Zain was named a Top 40 Under 40 Healthcare Innovator by MedTech and is a Scientific Advisory Board member for the American Gastroenterological Association Center for Gut Microbiome Research & Education. Dr. Kassam's research focuses on innovative microbiome-directed therapies that deeply impact human health and disease. He has authored over 100 peer-reviewed abstracts, publications and book chapters and holds grants from the CDC, CCFA and private foundations.
Dr. Kassam received his MPH degree with a focus on Clinical Trials at Harvard University on a Frank Knox Fellowship and completed his post-doctoral training in microbiome engineering at MIT. He completed both his Internal Medicine and Gastroenterology training at McMaster University, where he was the Chief Medical and Chief Gastroenterology Resident and was awarded the National Resident Leadership Award by the Royal College of Physicians and Surgeons of Canada.