OB Bottles.png

We are pleased to announce the release of our newest fecal microbiota transplantation (FMT) capsule formulation, FMT Capsule DE. Since the initial release of our G3 capsules in November 2015, we have been working with our contract manufacturer to improve the capsule formulation to better serve clinicians and patients.
The new DE capsules will replace our current G3 capsules, and will be available for shipment beginning June 18, 2018.

  • Changes from G3: DE capsules have two capsule shells, while G3 capsules are encased in a single gelatin capsule shell. The capsule contents have not changed. The DE capsule’s double layer includes an interior gelatin capsule shell and an acid-resistant external capsule shell. Dissolution assay testing demonstrates that DE capsules will remain intact through the stomach for longer than G3 capsules, allowing for more effective post-pyloric delivery of the microbiota. DE capsules also enable higher manufacturing yield rates than G3 capsules, which can improve the availability of capsules for patient treatment.


  • No change in ordering process or pricing: The process for ordering and storing capsules will remain the same, and the pricing will remain the same at $635 per dose (1 bottle, 30 capsules).

We are excited to provide this next generation of our capsule formulation to support you in your work to provide FMT treatment to patients. If you have any questions or concerns, please don't hesitate to reach out to us at info@openbiome.org or by calling 617-575-2201 x3 during our business hours, Monday-Friday, 9am-5pm EST. We look forward to hearing from you!

Reference Documents