Your stool can save lives.

We are seeking healthy volunteer donors to provide life-saving treatment for people with C. difficile infection. As a reimbursement for their commitment, donors are paid $40 per donation of stool.

Half a million Americans contract C. diff infections each year.  1 in 5 patients find that the infection comes back, even after they take antibiotics. For these patients, daily life gets hijacked by the disease.  30,000 people die from C. diff-related causes every year.

Where antibiotics have failed, a new treatment called fecal microbiota transplantation (FMT) made from donor stool cures patients 80%-90% after the first try. 

Who can donate?

Donors must be local to Cambridge or Somerville, Massachusetts and pass a series of health screens.  To begin the qualification process, they must be able to answer "yes" to the following questions:  

  • Can you make daily trips to our Cambridge or Somerville location for at least 60 days?
  • Will you be 18-50 years old during the donation period? 
  • Is your Body Mass Index (BMI) less than 30?

How does donating work? 

It's different than donating blood: our stool donors go through at least two rounds of rigorous screens that involve blood and stool tests. They must drop off donations five days a week for at least 60 days.

As compensation for this commitment, donors receive $40 for every stool they donate. 

The process: 

Join our Stool Donor Registry

When we need new donors, we reach out to members of the Stool Donor Registry and invite them to fill out a short health questionnaire.

We can only work with donors who are able to visit us in either Somerville or Cambridge, MA. We will not contact you for any other reason, and you may email us to remove yourself from the registry at any time.    

The Pre-Screen Interview

We invite qualified prospective donors to come to an OpenBiome location to meet with medical staff. During this visit, we run through a medical history questionnaire and interview similar to the one that blood donors answer. 

Blood and Stool Screening

Prospective donors who pass the clinical interview undergo a series of stool and blood screens to determine whether they have any potentially infectious pathogens. 

Donating Stool

Donors who pass the interview, stool test, and blood test are on board for a 60-day donation period! Our Somerville location is open Monday to Friday, 7am-6pm and Saturday - Sunday, 9am-3pm. Our Cambridge facility is open Monday to Friday, 6:30am-5pm and Saturday - Sunday, 8am-2pm. 

60-Day Follow-Up

After 60 days of donating, donors must undergo a second round of blood and stool screens. If they pass this round of screens, the stool we collected from them will be released and shipped to treat patients all over the country! Donors are welcome to keep donating for another 60 days, and many do. 


Ready to sign up?  Take the survey!